Product Name :
Rabbit anti-SLC11A2 Polyclonal Antibody(Center)
Synonym :
Natural resistance-associated macrophage protein 2; NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Solute carrier family 11 member 2; SLC11A2; DCT1; DMT1; NRAMP2
Host :
Rabbit
Species Reactivity:
Human, Mouse, Rat
Specificity :
This SLC11A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human SLC11A2.
Predicted Reactivity:
Applications :
WB~~1:2000
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Cardiovascular;Signal Transduction;Others
Background :
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
UniProt :
P49281
Additional information:
Product Details FAQ Citations(8) Video Pictures Documents |Overview |Synonym Natural resistance-associated macrophage protein 2; NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Solute carrier family 11 member 2; SLC11A2; DCT1; DMT1; NRAMP2 |Host Rabbit |Specificity This SLC11A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human SLC11A2. |Species Reactivity Human, Mouse, Rat |Applications WB~~1:2000 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit IgG |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Cardiovascular;Signal Transduction;Others |Target |Background Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria. |Cellular localization Endosome membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein |UniProt P49281 |References |References Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Tabuchi, M., et al. J. Cell. Sci. 123 (PT 5), 756-766 (2010) :Tabuchi, M., et al. Mol. Biol. Cell 13(12):4371-4387(2002) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-SLC11A2 Polyclonal Antibody(Center)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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