Within a longitudinal study.Author Contributions: Conceptualisation, A.M., S.B., R.S. and D.K.; methodology, A.M., R.S., S.B., G.L., E.M., T.P., A.K., J.S., A.U. and D.K.; software program, S.B.; validation by R.S., G.L., A.M., D.K. and S.B.; formal evaluation, E.M., T.P. along with a.K.; investigations, A.M., S.B., R.V., E.M., T.P., A.K., R.S. and D.K.; resources, R.S. and D.K.; data curation, R.S. and E.M.; writing for original draft preparation, A.M., S.B., R.S. and E.M.; writing for evaluation and editing, A.M., S.B., R.S. and E.M.; visualisation, S.B.; supervision, J.S., A.U., D.K. and R.S.; project administration by R.S.; and Pyronine B Autophagy funding acquisition by R.S. All authors have study and agreed for the published version from the manuscript. Funding: This research was funded by the Study Council of Lithuania (LMTLT) beneath project agreement No S-MIP-20-59; the principal investigator for the grant was Rasa Smaliukiene. Institutional Overview Board Statement: The study was approved by the Vilnius Regional Biomedical Research Ethics Committee, protocol No 2020/10-1275-754. Informed Consent Statement: Informed consent was obtained from all of these ML169 Autophagy subjects who were involved in the study. Data Availability Statement: The data supporting the reported benefits have been archived in the National Open Access Research Data Archive (MIDAS) at www.midas.lt, accessed on ten November 2021. Conflicts of Interest: The authors declare no conflict of interest. The funders had no part inside the style with the study; inside the collection, analyses, or interpretation of information; in the writing of the manuscript; or inside the choice to publish the outcomes.Information Availability Statement: The data supporting the reported benefits have already been archived within the Information Availability Statement: The information supporting the reported outcomes have been archived inside the National Open Access Research Information Archive (MIDAS) at www.midas.lt, accessed on ten November National Open Access Research Data Archive (MIDAS) at www.midas.lt, accessed on ten November 2021. 2021. Conflicts of Interest: The authors declare no conflicts of interest. The funders had no role within the Conflicts of Interest: The authors declare no conflicts of interest. The funders had no role within the design and style in the study; inside the collection, analyses, or interpretation of data; inside the writing from the manudesign of Int. J. Environ. Res. Public Health 2021, 18, 12239 the study; within the collection, analyses, or interpretation of data; within the writing in the manu14 of 18 script; or within the choice to publish the outcomes. script; or in the choice to publish the results.Appendix A Appendix AAppendix A(a) (a)(b) (b)Figure A1. The forward stepwise model choice method benefits presented for Model 1 right after automatic linear modelling: (a) Figure A1. The forward stepwise model choice method outcomes presented for Model 1 soon after automatic linear modelling: stepwise model choice strategy results presented for Model 1 after automatic linear modelling: Figure A1. The (a) the identified effects of the predictors on cortisol levels (CTL) by cortisone (CTN) and dehydroepiandrosterone (DHEA) (a) the identified effectsthethe predictors cortisol levels (CTL) by cortisone (CTN) and dehydroepiandrosterone (DHEA) and the identified effects of of predictors on on cortisol levels (CTL) by cortisone (CTN) and dehydroepiandrosterone (DHEA) and (b) the negative and constructive coefficient estimations that were identified for cortisone (CTN) and dehydroepiandrosandthe negative and and good coeffici.