Product Name :
MDM2-IN-1
Description:
MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.
CAS:
1410737-09-5
Molecular Weight:
463.33
Formula:
C23H21Cl2FN2O3
Chemical Name:
(3’R,4’S,5’R)-6”-chloro-4′-(3-chloro-2-fluorophenyl)-2”-oxo-1”,2”-dihydrodispiro[cyclohexane-1,2′-pyrrolidine-3′,3”-indole]-5′-carboxylic acid
Smiles :
OC(=O)[C@@H]1NC2(CCCCC2)[C@@]2([C@H]1C1=CC=CC(Cl)=C1F)C1=CC=C(Cl)C=C1NC2=O
InChiKey:
GQQZEPFAYBPYQU-GEQKSPFYSA-N
InChi :
InChI=1S/C23H21Cl2FN2O3/c24-12-7-8-14-16(11-12)27-21(31)23(14)17(13-5-4-6-15(25)18(13)26)19(20(29)30)28-22(23)9-2-1-3-10-22/h4-8,11,17,19,28H,1-3,9-10H2,(H,27,31)(H,29,30)/t17-,19+,23+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Pinacidil} MedChemExpress|{Pinacidil} Potassium Channel|{Pinacidil} Protocol|{Pinacidil} Formula|{Pinacidil} manufacturer|{Pinacidil} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Betrixaban} MedChemExpress|{Betrixaban} Metabolic Enzyme/Protease|{Betrixaban} Purity & Documentation|{Betrixaban} Formula|{Betrixaban} custom synthesis|{Betrixaban} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24605203
Additional information:
MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.|Product information|CAS Number: 1410737-09-5|Molecular Weight: 463.33|Formula: C23H21Cl2FN2O3|Chemical Name: (3’R,4’S,5’R)-6”-chloro-4′-(3-chloro-2-fluorophenyl)-2”-oxo-1”,2”-dihydrodispiro[cyclohexane-1,2′-pyrrolidine-3′,3”-indole]-5′-carboxylic acid|Smiles: OC(=O)[C@@H]1NC2(CCCCC2)[C@@]2([C@H]1C1=CC=CC(Cl)=C1F)C1=CC=C(Cl)C=C1NC2=O|InChiKey: GQQZEPFAYBPYQU-GEQKSPFYSA-N|InChi: InChI=1S/C23H21Cl2FN2O3/c24-12-7-8-14-16(11-12)27-21(31)23(14)17(13-5-4-6-15(25)18(13)26)19(20(29)30)28-22(23)9-2-1-3-10-22/h4-8,11,17,19,28H,1-3,9-10H2,(H,27,31)(H,29,30)/t17-,19+,23+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 22.5 mg/mL (48.56 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|